Exclusion criteria included any other medical diseases or use of medications known to develop osteoporosis or to affect bone mass.
Generally, fingolimod should not be used by patients with known cardiac arrhythmias or patients using other medications known to induce bradycardia.
Children with medical disorders, co-morbid psychiatric disorders or receiving medications known to affect sleep were not recruited.
Black boxes are typically reserved for medications known to have serious or life-threatening risks.
The complexity of the situation is also illustrated by the fact that elderly people more frequently take medications known to decrease the sphincter tone, which may promote reflux.
None of the subjects suffered from known metabolic or malignant diseases or were taking medications known to alter the adipose tissue metabolism.
Medication history prior to the ECG measurement and blood sampling, in particular medications known to affect the measurements clinically, was also recorded.
Medications known to induce CYP3A4/5, such as carbamazepine, were not permitted within 14 days before the baseline visit or during the study.
If the situation requires sedation, SRLF recommendations should be followed: lethal injections are prohibited but medications known to exert a double effect can be used.
The government is employing hundreds of military veterans as lab rats in drug tests, distributing medications known to have potentially severe side effects like psychosis and suicidal behavior.
In addition, they did not take medications known to affect brain function and did not have a history of alcoholism.
