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The use of nonsteroidal medication is prohibited.
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The use of non-steroidal medication was prohibited.
The use of other anti-allergy medication was prohibited.
† Concomitant administration of antidepressant medication was prohibited for the duration of the study.
No patients were treated with granulocyte colony-stimulating factor because the medication was prohibited on the study.
Patients were permitted to use rescue medication (acetaminophen ≤3 g/day) during the study, although use of rescue medication was prohibited from midnight before the baseline clinic visit.
Use of other ARBs as concomitant medication was prohibited, but other background medications (e.g. diuretics, calcium channel blockers) were allowed and continued throughout the study.
Concomitant use of such medication was prohibited in the reported trials, but it is reported that some patients used additionally other non- specified remedies.
Concomitant use of central nervous system medication was prohibited, except for limited use of select benzodiazepines/sedatives as needed for sleep.
The diet was balanced using the Harris Benedict equation and ingestion of alcohol or nicotine, excessive doses of caffeine, as well as the regular intake of any drug or medication was prohibited (details in Rittweger et al. 2006).
Because NETU is a moderate inhibitor of CYP3A4, use of any CYP3A4 inducer within 4 weeks, use of a strong or moderate inhibitor within 1 week or scheduled to receive CYP3A4 inhibitors, inducers or certain substrates as concomitant medication was prohibited (supplementary Table S1, available at Annals of Oncology online).
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