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The medication event rate was comparable to published rates on medicine services.
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Depending on the number of medication users and expected event rate, this may challenge the feasibility of some studies.
Recent research has shown that stimulant medication (methylphenidate) and shortened event rate can produce the same effect in a Go-Nogo task [ 58].
Greater disease severity may be potentially related to use of glucose-lowering medications and higher event rates, but requires further examination.
However, a recent cross-sectional glaucoma study in the USA found that participants with adherence rates < 80%, according to a medication event monitoring system (MEMS®), had worse visual field defects than those with adherence rates ≥ 80% [ 45].
However, three studies using objective methods like medication event monitoring system (MEMS) reported very low (31-39%) adherence rates [ 26- 28] which are comparable to our findings.
The adverse event rate and profile may be different in other centers which use other medications for PSA.
(n) Event rate (mean) Patients (n) Events.
CER, control event rate; EER, experimental event rate.
Reduction in event rate = Event rate with TIV − expected event rate with QIV.
Adherence will be measured using a medication event monitoring system.
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