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The purpose of this study was to determine whether parent health literacy and other variables predicted factors associated with adherence, such as missed medication doses, missed medical appointments, and seizure frequency, in children with epilepsy between 1 and 12 years old.
A patient self-report of adherence was also collected with patients reporting medication doses missed over the three preceding days at clinic visits.
Four adherence measures will form the basis of the self-reported ART adherence outcomes: (1) The AIDS Clinical Trials Group (ACTG) adherence questionnaire; which assesses patients' current ART medications, dosing schedule, and medication doses missed over the past four days [ 50 ]; (2) The Visual Analog Scale (VAS), which assesses general levels of adherence over a 30-day timeframe [ 51 ].
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The majority (89%) who had HIV and AIDS training and also 55 (61%) of those who had no previous training agreed that HIV can become resistant if ART medication doses are missed.
Although the most commonly reported reason for missed ARVT doses was forgetting to take medications, the modal proportion of doses missed was 100%.
At each clinic visit, the nurses or pharmacist will screen the patients for adverse events and ask the participants if they have missed any doses of their medication, and if so, the number of doses missed.
In the pre-intervention period, 75 medications for 37 (18.3%) patients had one or more doses missed or significantly delayed within 24 h of discharge from hospital.
This 30-day time frame for self-reporting medication adherence was previously validated and overcomes the challenge of remembering specific doses missed [ 71- 73].
For respondents who reported missing one or more doses of medication in the 48 hours before interview, we asked about the number of doses missed, and calculated the total proportion of doses taken.
The measure also consists of 2 multi-item scales to assess medication tension/worry (3 items regarding tension in administering and taking ADHD medication) and missed-doses worry (4 items regarding worry about the number of daily doses missed at home or school).
The following operational definitions were used: Medication administration error: A medication error (time, dose, missed drug, unauthorized, route, technique, and documentation errors) that occurs while the time of administering IV, IM, SC, and PO medication to the patient by the nurse.
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