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Since data on medication dose were not collected as part of the internet survey, all medication costs were estimated using daily dose assumptions based on the expert clinical opinion of the study authors who are also physicians.
Costs were not included in cases where medications referred to the treatment of infants, and Read codes not specifying medication dose were assigned the lowest unit price.
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Confounding-by-indication is a bias in nonexperimental studies that occurs when outcomes are compared for treated and untreated patients and the treatment or medication dose is related to predictors of the outcome.
When she relapsed, Eldred returned to her doctor, who determined her opioid maintenance medication dose was too low, and raised it, she recalled.
If dietary measures were insufficient to prevent postprandial hypoglycemia, the medication dose was reduced.
In cases where a medication dose was missing, a value of 1 DDD unit was assigned.
However, we found no evidence that medication dose was related to any of the circadian abnormalities.
If a medication order was dosed off a weight that had since been updated, a reminder to "weight adjust" the medication dose is issued.
The first medication dose was applied 24 h after infection, and, if repeated, every subsequent 24 hours for six days.
Study medication dose was a binary yes/no (1/0) variable indicating whether the participant was able to take the maximum (60 μg/meal) dose.
It would be ideal if the timing of a medication dose was not critical, such that occasionally missing a dose would not have a negative impact.
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