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Taking a medication class was defined as taking any drug within the medication class per day.
Medication class was not associated with TNFα levels (overall p = NS; data not shown).
Use of medication class was not limited by study assignment.
The most frequently studied medication class was low molecular weight heparin in 53 studies (79%).
This medication class was also the most commonly used medication classes among all study participants.
In addition, each medication class was treated as time-dependent covariates in the model.
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In this modeling, associations between variable cluster analysis-identified chronobiological characteristics and both gender and medication class were noted (Table 4).
Doses are intensified or a new medication class is added every month if HbA1c levels are ≥6% or if >50% of premeal or postmeal capillary glucose readings are >5.6 mmol/L (100 mg/dL) or >7.8 mmol/L (140 mg/dL), respectively.
Prescribing time patterns of each antihypertensive medication class were also explored.
In conclusion, the incretin medication class is currently approved as monotherapy or combination therapy in adults with T2DM and has been shown to be beneficial in glucose management and the achievement of HbA1c goals.
Although there are no discrete studies establishing clinical benefit for CRS in the CF population, similar CF-related pathophysiology between the sinonasal and pulmonary airways indicates this medication class is likely a valuable therapeutic addition for CF-associated sinus inflammation.
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