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Four studies showed that medication adherence did not improve with delivery to the patient of educational materials such as leaflets, letters, or automated telephone calls [176, 177, 178].
Study medication adherence did not differ across treatment arms or by sex, but specific data regarding adherence to ACE inhibitor therapy were not collected.
In an adult population, medication adherence did not fully explain elevated A1C observed in African American compared with white patients (44); thus, it is possible that biological as well as social and behavioral factors contribute to suboptimal glycemic control among African American individuals.
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However, these quantitative studies focused on hypertensive medication adherence and did not focus on hypertensive treatment adherence or factors affecting adherence (26, 27).
However, current medication use and self-reported adherence did not improve the model fit, suggesting that such preferences are formed independent of self-reported medication-taking behaviour.
Interestingly, supplying the treating clinician with information regarding medication adherence patterns does not influence patients' medication beliefs, nor does it engender any changes in adherence [ 52].
This suggests that better systems approaches are needed to improve medication adherence that do not rely on individual PCPs.
There was one prospective observational study that had a low-moderate sample size where the authors' were able to demonstrate an important relationship between health literacy and medication adherence, but they did not provide the percent of parents that had limited or marginal health literacy, therefore it scored lower as a IIIB [ 17].
It is accepted that MPR may overestimate medication adherence as it does not confirm ingestion or inhalation [ 8].
Whether written prescriptions were filled by the patients and the level of medication adherence among patients who did fill the prescriptions is unknown.
However, more recent studies either did not examine AIDS-defining diagnosis as an HIV medication adherence predictor [ 20] or did not find an association [ 21].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com