Sentence examples for mediators which may from inspiring English sources

Potential modifiers and mediators, which may mitigate or amplify the impact of overweight or obesity in individuals, include coping strategy/personality type, comorbidities, age, gender, and weight class.

The mediators which may underlie the deleterious effects of depression in patients with renal disease, and their relationship with stage of renal dysfunction have not been delineated.

Axons are sensitive to mechanical injury and toxic inflammatory mediators, which may lead to demyelination.

In addition to being converted to potent inflammatory lipid mediators, which may independently contribute to the increased atherosclerosis of smLRP−/− mice by promoting macrophage recruitment, arachidonic acid is itself a key regulator of cellular signaling.

Our findings reinforce the idea that Thy-1 expression in fibroblasts modulates their responses to inflammatory mediators, which may account for the more severe lung fibrosis in Thy-1 deficient mice and the predominance of Thy-1− fibroblasts in the fibroblastic foci in patients with idiopathic pulmonary fibrosis [19].

Eosinophils produce dozens of mediators which may be selectively released and which have varying physiologic actions.

In addition to causing local tissue destruction, periodontitis also elevates circulating levels of inflammatory mediators [5] [8], which may contribute to the development of systemic diseases such as cardiovascular diseases [9].

These two subunits are present in the C- and L-Mediator complexes, which may act as positive and negative regulator of transcription, respectively [32].

Membrane-bound FasL can be cleaved and released as a soluble mediator (sFasL), which may spread the apoptosis induction effect.

Activation can lead to dilation of intracranial vessels, plasma protein extravasation and local dural release of inflammatory mediators [23, 24], which may lead to a cascade of events that ultimately produces activation of dural-trigeminovascular neurons (see Figs. 1 and 2).

Finally, we were able to demonstrate that the phenotype of skeletal muscle in ICU patients is not merely one of inactivity, it appears to be an actively remodelling tissue, influenced by several mediators, all of which may be open to manipulation with the aim to improve clinical outcome.