Sentence examples for mediators which can from inspiring English sources

Intriguingly, AFODN4 inhibited AP-1-mediated production of proinflammatory mediators, which can be caused by blockage of SMAD alone in vitro and in vivo.

For example, shock induces gut hypoperfusion, leading to production of proinflammatory mediators, which can amplify the SIRS response [ 13].

CNS cells can be subjected to a variety of stressors (e.g., toxins, oxygen radicals, and inflammatory mediators), which can change the immune status of the CNS [ 3].

Black liquors from pulp cooking constitute low-cost sources of natural mediators which can be applied in laccase-mediator systems for Totally-Chlorine-Free bleaching of paper pulps [ 16].

Thus, over time, the blood purification concept and therapies have evolved toward the non-specific removal of a broad spectrum of inflammatory mediators, which can also include microbial toxins.

Furthermore, extracellular HMGB1 can induce the release of proinflammatory mediators, which can result in highly increased serum levels of proinflammatory cytokines, and then cause the activation of immune system, as well as invasion by inflammatory cells, thereby prolonging and sustaining inflammatory processes [ 42].

Subjective support is a measurement of the perceived support available to an individual; it is a mediator variable which can influence his/her behavior [ 54].

Undergoing systemic inflammation, the innate immune system releases excessive proinflammatory mediators, which finally can lead to organ failure.

Structural disruption of the lung caused by mechanical ventilation (barotrauma and volutrauma) includes a component of associated mediator release (biotrauma) which can further aggravate lung injury and potentially lead to systemic multi-organ failure [ 6- 10].

Microglial cells are able to produce and release a plethora of soluble mediators ranging from cytotoxic mediators to trophic factors, which can exert deleterious as well as beneficial effects on the surrounding tissue.

Since the salivary transcriptome was clearly altered in tumor-bearing vs. control mice, we hypothesized that the tumors behave like endocrine organs in that they secrete mediators (hormones, lymphokines, cytokines) which can affect the activity of TF in salivary glands and thereby induce up or down-regulation of transcripts levels in saliva.