Sentence examples for mediators to stimulate from inspiring English sources

Inhibition of calcium signaling, NFATc1 activation, and ERK1/2 phosphorylation significantly reduced the ability of prostate cancer mediators to stimulate osteoclastogenesis.

Antisense transcription upstream of the COX-2 transcription start site was indeed detected in HCT116 cells in the recent study [Galbraith, M.D., et al., HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia. Cell, 2013. 153 6): p. 1327-39.].

Transforming growth factor β (TGF-β) is a major fibrotic mediator known to stimulate fibrosis.

These mature microvascular networks were treated with phorbol-12-myristate-13-acetate phorbol-12-myristate-13-acetate phorbol-12-myristate-13-acetate phorbol-12-myristate-13-acetate phorbol-12-myristate-13-acetateascular networks induced raPMA adhesion and aggregation of platelets whichn misutes, which first obstructed the lumen but were then shed into the flowing blood.

In UACS secretions containing inflammatory mediators are thought to stimulate proximal airway receptors inducing cough.

A number of proinflammatory mediators are known to stimulate megakaryocyte proliferation [ 18].

It is therefore possible that any new therapy that aims to raise the levels of HMGB1 or other inflammatory mediators in order to stimulate tissue repair in one tissue might also lead to unwanted effects in other tissues.

We have also found that LPA can stimulate ROS generation in breast cancer cells, which may serve as an important mediator for LPA to stimulate breast cancer cell migration through the activation of PI3K/PAK1/ERK signaling pathway.

These cells release a wide variety of cytokines and mediators that have the capacity to stimulate other resident cells such as smooth muscle cells and fibroblasts.

This module includes pro-inflammatory mediators such as IL1β, which is known to stimulate Th17 differentiation [44], and IL1F8, which stimulates pro-inflammatory mediators in fibroblasts [45], but also anti-inflammatory cytokines such as IL-1F5, which actually inhibits inflammatory skin disease [46], as well as the IL1 receptor antagonist (IL1RA).

IL-1β is also known to stimulate many proinflammatory mediators in a variety of cell types [ 32].