Sentence examples for mediators that induce from inspiring English sources

This may result from a local IL-7-induced increase in proinflammatory mediators that induce cartilage destruction, such as TNF-α and oncostatin M. IL-7R blockade has been demonstrated to reduce local expression of such cytokines, thereby preventing cartilage destruction [ 19].

I/R-induced cardiovascular failure is traditionally ascribed to the effects of inflammatory mediators that induce circulatory changes with resulting tissue hypoxia and cell damage [ 22].

These cells produce mediators that induce the formation of fibroblast and myofibroblast foci through the proliferation of resident mesenchymal cells, attraction of circulating fibrocytes, and stimulation of the epithelial to mesenchymal transition.

MPO, a marker for the presence of neutrophils, was strongly correlated with IL-8 and G-CSF, mediators that induce neutrophil migration and support neutrophil function, respectively.

Important mediators that induce immunogenic cell death include HMGB1, calreticulin and fragments of polynucleotides induced by chemoradiation.

Vascular endothelial growth factor is the most potent of the numerous mediators that induce endothelial cell functions and facilitate new vessel formation.

Longer cultivation of CCH (44 h) increased the number of metabolically active wells and in addition to adenosine revealed another 20 hormones/immune mediators that induced metabolic activity of CCH44 (Table 2).

In this reaction, PAF rather than histamine was the major chemical mediator that induced systemic anaphylaxis (Tsujimura et al, 2008).

Ceramide is also a lipid mediator that induces programmed cell death, differentiation, senescence, cell cycle arrest, and autophagy.

It is unknown whether lysophosphatidic acid, a multifunctional lipid mediator that induces cell proliferation, migration and survival, is also directly transferred [ 31].

LPS is a potent and predominant microbial mediator that induces an intense inflammation and procoagulant response, which are closely correlated events.