Sentence examples for mediators that enhance from inspiring English sources

Mast cells thus rapidly and selectively produce appropriate mediators that enhance effector-cell recruitment and complement other effector components of the immune system [9].

In response to lung damage, leukocytes and tissue-resident cells were reported to interact to generate lipid mediators that enhance the airway immune response and engage defense mechanisms.

Leptin is also a pro-inflammatory mediator that enhances systemic and pulmonary inflammation [ 42].

However, indirect observations suggest that astrocytes may help augment pericyte proliferation through augmentation of PDGFβ levels [ 165] or release of inflammatory mediators [ 166] that enhance gliosis.

Although mast cells contain other inflammatory mediators that could enhance Cox-2 production by fibroblasts [ 30], our findings implicate TGF-β1 as a mast cell-derived cytokine, which significantly enhanced the production of Cox-2 and PGE2 by tendon fibroblasts.

It is generally accepted that proinflammatory cytokines such as IL-1, TNF- α, and IL-6 are key mediators that greatly enhance the synthesis and secretion of MMPs [ 39].

These Th1 cells produce inflammatory mediators such as IFN-γ, that enhance macrophage effectors functions against intracellular pathogens [ 8].

A genomic region containing a group of putative enhancers in close genomic proximity with unusually high levels of transcription factor and mediator co-activator binding that enhances gene transcription.

Together with PGE2, another inflammatory mediator that is enhanced significantly in TB mice, these cytokines play a central role in the induction of the immune suppression observed in these tumour-bearing mice (Young, 1994).

The simplified picture suggests that eicosanoids are pro-inflammatory mediators that act locally to enhance vasodilatation and increased permeability of venules.

In RA, synoviocytes are key players in the production of inflammatory mediators and proteases that subsequently enhance the inflammatory process and joint damage [ 13- 17].