Sentence examples for mediators that damage from inspiring English sources

Various clinical situations such as pulmonary haemorrhage, meconium aspiration syndrome (MAS), pulmonary infection and atelectasis have been shown to liberate inflammatory mediators that damage type II pneumocytes and inactivate surfactant [ 20, 21].

Furthermore, microvascular perfusion could be disrupted by circulating inflammatory mediators that directly damage the peripheral vascular bed.

We anticipate that an unbiased genetic screen to identify such factors that can support survival when Chk1D469G is present in single copy may reveal additional mediators that contribute to damage specific checkpoint responses.

6 Deposition of urate crystal material in vessel walls has been proposed to cause neutrophil and platelet activation and release of inflammatory mediators that promote cardiovascular damage.

Pathogens can be defined as microbes capable of causing damage to the host, and virulence factors defined as mediators which enable that damage to occur (Casadevall and Pirofski 2001).

Synovitis develops only at later stages and may be triggered by mediators that result from cartilage damage, such as matrix degradation products or chondrocyte-derived cytokines [ 20].

Chronic infections are involved in the etiopathogenesis of many systemic diseases by releasing pro-inflammatory mediators that may cause endothelial damage and initiate, for example, cholesterol plaque attachment (for review, see [ 10]).

MV causes injury not only by structural disruption of the lung but also by inducing the release of mediators that can worsen lung damage and may cause multiorgan dysfunction [ 2].

Instead, monocyte-derived macrophages (MDMs) and parenchymal microglia are the productively infected cells within the brain [2], [3], and it is the viral proteins and inflammatory mediators released by these cells that damage neurons either directly or by causing glial dysfunction (reviewed in [2], [4].

Endothelial damage may be a common mechanism when vascular damage is present, although diverse mediators can be responsible for that damage, including antiphospholipid antibodies.

This modification in vivo would scale down the release of inflammatory mediators that would prevent progressive live damage.