Sentence examples for mediators of which from inspiring English sources

T cell priming by professional antigen presenting cells is tuned by an orchestra of inflammatory mediators, of which TGFβ, IL-23, IL-6, IL-22 and IL-1α are considered the most influential.

This concordance suggests that both responses are determined by the same set of mediators of which IL-1 isoforms appear to be involved.

Although lymphocytes in adaptive immunity are well understood, their role in innate immunity and resolution is highlighted here, as is their functional control by lipid mediators, of which there is a growing body of evidence.

That panel consisted of 15 mediators, of which interleukin 6 (IL-6), IL-8, monocyte chemoattractant protein 1 (MCP-1) and macrophage inflammatory protein 1β (MIP-1β) could be measured reproducibly from the explant cultures.

They alter the production of inflammatory eicosanoid mediators of which they are precursors, directly affect the organization and properties of the immune cell membranes with effects on signalling pathways, phagocytic capacity and antigen presenting capability, and activate transcription of various genes involved in inflammatory responses.

After IV infection they release a cascade of immune mediators, one of which is granulocyte and macrophage colony-stimulating factor (GM-CSF).

This process involves the recruitment of mature vasculature and circulating endothelial cells and proangiogenic soluble mediators, one of which includes the vascular endothelial growth factor (VEGF).

The inflammatory cascade involves large numbers of inflammatory cells and mediators, many of which are directly produced in the lung.

Our model was able to predict the effects of altered pathway components and synergistic combination of multiple mediators, some of which are consistent with experimental findings [ 73].

Articular tissues are capable of producing a range of eicosanoid mediators, each of which has individual biological effects and may be affected by anti-inflammatory treatment.

However, chondrocytes have been shown to produce a host of cytokines and inflammatory mediators, many of which are also produced by monocytes/macrophages [ 27].