Sentence examples for mediators of protein from inspiring English sources

Biochemical studies of purified and recombinant Arfs have revealed them to be regulatory GTPases that act as allosteric activators of several enzymes, including the ADP-ribosyltransferase activity of some bacterial toxins and mammalian lipid-modifying enzymes, and mediators of protein complex assembly, particularly in the biogenesis of carriers of membrane traffic.

The RPA70N and -32C domains are the primary mediators of protein interactions.

LATs have been shown to be critical mediators of protein translation and cell growth in a variety of cancers.

Members of the HSPA (HSP70) and DNAJ (HSP40) chaperone families are major mediators of protein quality control (Kampinga and Craig, 2010).

Stress-inducible HSP70 and DnaK proteins are critical mediators of protein quality control that have been implicated in several human diseases.

Primary outcome: mean fiber area and fiber type composition measured by histochemical analyses, satellite cells and levels of protein and mRNA expression of intracellular mediators of protein turnover.

Leucine zippers [1] are parallel alpha-helical coiled coil motifs and as such one of the most common mediators of protein-protein interactions [2].

VCP is a member of the AAA family of ATPases and is a critical mediator of protein homeostasis [ 8].

Valosin containing protein (VCP) is a critical mediator of protein homeostasis and may represent a valuable therapeutic target for several forms of cancer.

It has also become clear that the linear sequence of nucleic acid bases is not only the mediator of protein recognition, but also of higher-order structure of DNA and its associated molecules and chemical modifications.

The decrease in phosphorylated Akt (S478), in conjunction with Foxo3a inactivation and activation of mTOR signalling, demonstrates that Akt is not the sole mediator of protein synthesis or degradation in skeletal muscle during hibernation.