Sentence examples for mediators of programmed from inspiring English sources

Vacuolar processing enzymes (VPEs) are cysteine proteinases that act as crucial mediators of programmed cell death (PCD) in plants.

Lysosomal cathepsins function as effective mediators of programmed cell death but the pathways leading to LMP are, however, poorly understood.

Caspases are crucial mediators of programmed cell death (apoptosis).

In addition, there is increasing recognition that caspases have numerous functions in addition to their roles as mediators of programmed cell death.

Finally, our study has confirmed and extended the role of ceramide as one of the key mediators of programmed necrosis downstream of RIPK1 and RIPK3 to the clinically more relevant tumor cell systems investigated here, with the A-SMase inhibitor Arc39 additionally validating A-SMase (rather than neutral sphingomyelinase or ceramide synthase) as the main enzyme responsible for ceramide generation.

In this study the effectiveness of OVK will be tested and possible mediators of program effects will be focus of study as well.

In a previous study, we had identified ceramide generated by the lipase A-SMase as an important mediator of programmed necrosis acting downstream of RIPK1 [ 3].

Complementary analysis suggests that self-assessed relative poverty (as measured by comparison to other households in the community) is a more important mediator of program effects on happiness than absolute poverty (as measured by household consumption expenditures).

This review will discuss maternal metainflammation as a mediator of programming in insulin sensitive tissues in offspring.

One class of genes that has been considered a potential target or mediator of programming events is imprinted genes, because these genes critically depend upon epigenetic modifications for correct expression and because many imprinted genes have roles in controlling fetal growth as well as neonatal and adult metabolism.

A set of genes that has received a great deal of interest as possible mediators of developmental programming effects are imprinted genes.