Sentence examples for mediators of matrix from inspiring English sources
To compare the effects of two hyaluronic acid (HA) formulations on mediators of matrix turnover and inflammation in an IL-1-treated cartilage synovium co-culture model with the aim of elucidating mechanisms by which viscosupplementation exerts beneficial effects in osteoarthritic joints.
These matrix fragments can stimulate production of multiple mediators of matrix destruction, including various cytokines and metalloproteinases.
50 Enhanced liver fibrosis (ELF) panel employs automated immunoassay of three serum markers of matrix constituents and mediators of matrix remodeling (hyaluronic acid, amino-terminal propeptide of type III collagen, and tissue inhibitor of matrix metalloproteinase 1).
ROS and RNS damage cellular elements in cartilage directly and damage components of the extracellular matrix either directly or indirectly by upregulating mediators of matrix degradation (reviewed in [ 2, 26]).
This has shown that MDPs are the key mediators of matrix degradation in the NP, but that matrix degradation in the AF is mediated by both MDPs and serine/cysteine proteases.
FN might play a role in articular cartilage destruction, because it has been observed that FN fragments can stimulate the production of multiple mediators of matrix destruction, such as various cytokines and metalloproteinases [ 46, 47].
Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis.
Urokinase plasminogen activator (uPA) is an important mediator of matrix degradation and invasiveness of cancer cells [ 36].
TSP1 is a key mediator of matrix contraction of normal and systemic sclerosis fibroblasts, via MEK/ERK.
In this study, we specifically targeted IL-1β because this cytokine has been implicated as a primary mediator of matrix catabolism in disc degeneration.
Relaxin, a 6-kDa polypeptide hormone, is a potent mediator of matrix turnover and contributes to the loss of collagen and glycosaminoglycans (GAGs) from reproductive tissues, including the fibrocartilaginous pubic symphysis of several species.
