Sentence examples for mediators of ischemic from inspiring English sources

In this study, we examined downstream mediators of NO/PARP activation to investigate possible mediators of ischemic sexual dimorphism.

These studies, in turn, are the outgrowth of three decades of investigative work to define the multiple mechanisms and mediators of ischemic brain injury, which constitute potential targets of neuroprotection.

These channels are well known mediators of ischemic cardioprotection promoted by preconditioning or other known cardioprotective drugs [2], [12].

Finally, we measured the expression of several antioxidant genes that have been proposed as potential mediators of ischemic preconditioning [64], [77], [78] because METH toxicity involves the production of reactive oxygen species [2], [79].

Neutrophils are known to be critical mediators of ischemic reperfusion injury after organ transplantation.

However, calcium ions are also intracellular mediators of ischemic damage [ 13].

Nitric oxide, a product of nitric oxide synthase activation, is an important mediator of ischemic brain injury [38].

We also measured the expression of brain derived neurotrophic factor (BDNF) which is thought to be a mediator of ischemic preconditioning [64], [65], [68], [69] and of glial cell line-derived neurotrophic factor (GDNF) which is known to exert protective effects against METH-induced toxicity [70] [72].

Nitric oxide (NO) is cardioprotective and a mediator of ischemic preconditioning (IP).

S1P is claimed to be the principal mediator of ischemic pre- and post-conditioning [ 24, 25, 54].

Our data indicate a cardiac protective role of DDFPe that persists beyond its retention time in the body and is dependent on mitoKATP, an important mediator of ischemic preconditioning induced cardiac protection.