Sentence examples for mediators of intercellular from inspiring English sources

They are important mediators of intercellular communication and regulators of the cellular niche, and their altered characteristics in many diseases, such as cancer, suggest them to be important both for diagnostic and therapeutic purposes, prompting the idea of using exosomes as drug delivery vehicles, especially for gene therapy.

Previously believed to be inert cellular debris, microvesicles are now gaining acceptance as important mediators of intercellular communication [2] [9].

The AJs are key mediators of intercellular adhesion and lie just basal to the SAR.

Microparticles (MPs) are small circulating membrane-coated vesicles that are important mediators of intercellular signaling.

Recently, accumulating data have suggested that EVs are in fact crucial mediators of intercellular communications.

Exosomes are mediators of intercellular communication that can deliver information from cell to cell [ 66].

Microvesicles (MV) have been proved to be an important mediator of intercellular communication and can selectively transport secreted microRNA from a donor cell into a recipient cell.

Extracellular calcium is known to be a key mediator of intercellular contacts, with concentrations greater than 1 mM resulting in stable adherens junctions mediated by the homotypic interaction of E-Cadherin molecules expressed on the membranes of adjacent cells [ 21].

Finally, investigation of the production of MPs at a local level in the target organs of autoimmunity, such as salivary glands in pSS, could be helpful for better understanding the role of these vesicles as mediators of the intercellular cross-talk.

They play a role of intercellular mediators, setting cell growth processes and participating in their differentiation, migration, and apoptosis [ 11, 12].

Do TPR GoLoco proteins function as conserved, spatially regulated mediators of spindle orientation by intercellular signaling?