Sentence examples for mediators of immunity from inspiring English sources

Nuclear factor-κB (NFκB) transcription factors, which play major roles as mediators of immunity and inflammation, are expressed in skeletal muscle, where they mediate the effect of inflammatory cytokines on muscle wasting and cachexia.

NFκB transcription factors, which play major roles as mediators of immunity and inflammation, are also expressed in skeletal muscle, where they mediate the effect of inflammatory cytokines, particularly tumor necrosis factor-α (TNFα), on muscle wasting and cachexia (reviewed in Peterson et al., 2011) (Fig. 3).

In the absence of multiple mediators of immunity, we hypothesized that the role of neutrophils during influenza virus infection could be studied more effectively.

Studies of immune responses in cattle immunised by infection and treatment have provided evidence that MHC-I restricted CD8+ T cells, which are able to kill parasitised lymphoblasts, are important mediators of immunity [8], [9].

Dendritic cells (DCs) are professional antigen presenting cells and are essential mediators of immunity and tolerance.

This suggests that tifacogin interacts with a blood component, such as cellular mediators of immunity.

Research confirms that the most important mediator of immunity to EPM is interferon-gamma, while the humoral immune system also contributes via inactivation of specific protozoal surface proteins.

Mtb triggers host type I interferons signaling to reduce the production of interleukin-1β (IL-1β), a critical mediator of immunity to Mtb (Novikov et al., 2011).

Objective: To determine the induction of tumour necrosis factor-alpha (TNFα), a central mediator of immunity, by human monocytes infected with virulent M. tuberculosis, M. leprae and attenuated M. bovis BCG.

Recently, IL-17 became the focus of research because it was identified as a major mediator of immunity and inflammation, such as in RA, multiple sclerosis and other disorders [ 1, 48].

In addition to the humoral immune response, serum levels of mediators of cellular immunity may also be suitable for elucidating immune mechanisms underlying the outcome of an infection.