Sentence examples for mediators of general from inspiring English sources

In total, these results implicate a small number of genes, particularly a cluster related to dopamine D1 signalling in the PFC, as being related to and potentially as being mediators of general cognitive abilities (c.f., general intelligence).

Representative images can be found in Additional files 3 and 4. We have employed 4T1 breast cancer subpopulations, derived from primary mammary tumors or bone, lung and liver metastases, to identify potential mediators of general or organ-specific breast cancer metastasis.

ClpP is a central mediator of general and regulatory proteolysis in bacteria.

Reactive oxygen species are, in fact, general mediators of cell damage (Kehrer, 1993) and their generation is a prerequisite for the triggering of cell death by several stimuli, including growth factor withdrawal (Palazzotti et al, 1999) and activation of the tumour suppressor protein p53 (Polyak et al, 1997).

Experimental studies that were conducted in isolated primary hepatic cells and experimental animal models led to the identification of general pathogenetic mediators––signalling pathways that are involved in the fibrogenic response.

In all other studies, including this study, growth conditions included a constant temperature >16° and long and nonchanging photoperiods sufficient to saturate the photoperiodic pathway, thus allowing the emergence of effects caused by general mediators of flowering time and providing an explanation for the absence of clock-associated loci in our list of QTL.

Moreover, recent identification of lupus risk factor genes with functions in interferon responses (Graham et al. 2007) and as more general mediators of innate immune signaling, as in the case of STAT4 (Remmers et al. 2007), suggests that innate immune pathways subject to environmental influences in addition to TLRs may prove to be relevant to lupus pathogenesis.

The purpose of this book is to provide an introduction to the cell types, chemical mediators, and general mechanisms of the host's first response to invasion.

Smed-med7 and Smed-med27 belong to a mediator complex essential for the assembly of general transcription factors.

Previous studies confirmed high levels of IL-6 in the synovial fluid in the acute phase after ACL injury and the IL-6 type cytokines are an important family of mediators involved in general inflammation and healing response.

The second group consists of general cofactors such as the Mediator complex and the SAGA complex (Timmers and Tora, 2005).