Sentence examples for mediators of breast from inspiring English sources

Another approach was used by Kang et al. in order to find mediators of breast cancer metastasis to bone by using MDA-MB-231 cells [31].

These data indicate that the genes identified by the HIS are potentially important mediators of breast cancer invasion and dissemination.

PTHrP is one of the major mediators of breast cancer related hypercalcemia and osteolytic bone metastasis [ 41].

This investigation may be particularly important because several mediators of breast cancer signaling and tumorigenicity, in addition to Mcl-1, are regulated by USP9X.

Women that have been exposed to TCDD can expose their children to TCDD through maternofetal transfer and/or breast-feeding, further increasing the risk of exposure to environmental mediators of breast cancer during key developmental windows of susceptibility.

HGF and its receptor, C-MET, are both critical mediators of breast cancer progression, and, like in many other solid organ cancers, both HGF and C-MET are highly expressed in breast cancer [ 2– 5].

Additionally, bone metastasis lesions-derived TGF-β can serve a critical mediator of breast carcinoma-mediated progression of osteolytic bone lesions, and the effector of this response is PTHrP.

This study identifies SPSB1 as a critical mediator of breast cancer recurrence, suggests activation of the SPSB1-c-MET pathway as an important mechanism of therapeutic resistance in breast cancers, and emphasizes that pharmacologic targets for recurrence may be unique to this stage of tumor progression.

Cancer-associated fibroblasts (CAFs) are crucial co-mediators of breast cancer progression.

The ER is the primary mediator of breast cancer proliferation in response to oestrogen.

Our data suggest that ABCC5 functions as a mediator of breast cancer skeletal metastasis.