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Recent data have also demonstrated that lipid mediators may influence the action of oestrogens (Sukocheva et al, 2009).
In fact, many inflammatory mediators may influence cell proliferation and tumor development, as demonstrated by our recent studies on annexin A1 [ 18- 20].
The articles contained in this special issue of Gut Microbes have been authored by world-class investigators and provide fresh insights into specific mediators of H. pylori-induced disease and, importantly, how such mediators may influence strategies for the prevention, diagnosis and treatment of oncogenic consequences stemming from infection.
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In addition, the prognostic relevance of Wnt5a methylation may be confounded by the status of downstream canonical and non-canonical Wnt mediators that may influence the signalling response to Wnt5a loss.
68 Alternatively, researchers make additional random allocations between options that are not therapeutic in their own right, but may influence mediators; 69 for example, enhancing the therapeutic environment may enhance alliance (the mediator), but have no direct effect on symptoms (the outcome).
Mechanical stress can induce biochemical and functional changes in cartilage that may influence mediator production.
IL-6 and S-100B are considered to be important mediators for the pathophysiology of PCAS and TH may influence blood levels of these mediators.
These results illustrate discrepant tissue-specific effects of RAS stimulation on cisplatin nephrotoxicity and raise the concern that inflammatory mediators produced by renal parenchymal cells may influence the function of remote organs by altering systemic cytokine levels.
Compromised epithelial integrity, the elaboration of local proinflammatory mediators, and dysfunction of neural pathways may influence airway responses to environmental stimuli.
Hypoxia and reoxygenation can affect cytokine-induced proinflammatory mediator production, suggesting that oxygen tension may influence inflammation associated with cartilage injury and disease.
Genetic polymorphisms may influence the production of inflammatory mediators and predispose to different disorders, including diabetes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com