Sentence examples for mediators in several from inspiring English sources
We show that desired behaviors, which are stable against deviations by coalitions, can be obtained using mediators in several classes of settings.
Thus, animals treated with PARP-1 inhibitors or PARP-1 deficient mice showed decreased tissue damage and inflammatory mediators in several models of ischemia-reperfusion and heart transplantation (reviewed in [9]).
Recently, increasing evidence has demonstrated that oxidative stress (ROS generation) also plays a key signaling molecule in regulation of various inflammatory mediators in several cell types.
Pro-inflammatory cytokines, for example, TNFα, IL-18, IL-12 and IL-23, released from M1-like macrophages have been identified as important mediators in several autoimmune diseases.
PLA2s are multifunctional proteins that can be used as mediators in several areas of medicine, such as in the treatment of rheumatoid arthritis, as a new class of HIV inhibitors by blocking the host cell invasion, as a potential treatment against malaria, and as an antibiotic by inducing cytotoxicity via the disruption of bacterial membranes [ 21, 23, 30, 67, 68].
Its relevance as a mediator in several pathologic states and the aging process together with its transient character and low steady-state concentration, motivated the development of a variety of techniques for its unambiguous detection and estimation.
Besides regulating Arp2/3-based cortical actin networks by direct interactions, cortactin also functions as a key mediator in several kinase-based signal transduction cascades that indirectly govern Arp2/3 activity and cell movement.
HMGB1 has been increasingly recognized as a pathogenic mediator in several inflammatory diseases.
This indicates that CA VA can act as a key mediator in several metabolic pathways of the liver.
IL-1 β is a proinflammatory cytokine and an angiogenic mediator in several systems in diabetic patients, including the aqueous humor, vitreous, and tears [ 29, 30].
Interestingly, GSK-3 importantly regulates multiple proteins implicated in migration and is an important mediator in several of the signaling pathways involved.
