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Following injury a variety of endogenous mediators are released which mediate the cardinal signs of inflammation: heat, redness, swelling, and pain.
Both pro-nociceptive and antinociceptive mediators are released in the tissues during inflammation.
In the course of peritonitis multiple inflammatory mediators are released locally, including IFNγ and TNFα [33], [34], [36], [37].
During acute synovitis, algogenic mediators are released from extravasated immune cells and primary afferent nerve terminals.
Inflammatory mediators are released from injured epithelium, leading to both platelet activation and inflammatory cell migration.
During the neurogenic inflammation, neuropeptides [ 8] and cytokines and other mediators are released [ 9].
Similar(29)
A cascade of cytokines, growth factors, and other soluble mediators is released immediately following injury to orchestrate the repair of complex tissues [ 119].
In this paper, we have shown that the magnitude of degranulation responses is enhanced by FcγRIII activation, but we don't expect that the calcium flux-dependent processes initiated by FcγRIII would result in different mediators being released.
Endothelin-1 is produced by airway epithelial cells (Fig. 4A), and increased levels of this mediator are released into the airways of AdS OVA mice (Fig. 4B).
Soluble mediators that are released from dengue virus-infected monocytes/macrophages strongly affect the biological characteristics of endothelial cells and the hematopoietic cell population, indicating that the interactions between dengue virus and monocytes/macrophages are important in the pathogenesis of DHF/DSS.
Both cough and itch also involve mast cells and their mediators, which are released upon degranulation.
More suggestions(15)
mediators are produced
mediators are involved
mediators are selected
mediators are known
mediators are introduced
mediators are shown
mediators are clustered
mediators are synthetized
mediators are suggested
mediators are brought
mediators are listed
mediators are depicted
mediators are implicated
mediators are associated
mediators are thought
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