Sentence examples for mediator upon from inspiring English sources

In the brain's draining lymph nodes (cervical lymph nodes, cLN), CR mice contained significantly fewer CD8+ and CD4+ T cells able to produce IFNγ, a critically important antiviral mediator, upon ex vivo peptide stimulation (Fig. 5B, C).

In the procedure, a mixture of holoenzyme and free Mediator and RNA Pol II are affinity captured, with release of free Mediator through TEV cleavage (panel B ) and subsequent release of holoenzyme and free Mediator upon 3C protease cleavage (panel C ).

Tpl2-/-macrophages produce less inflammatory mediators upon lipopolysacharite (LPS) stimulation [29], and Tpl2-/-mice are resistant to LPS-induced shock [28].

The phenotype of lung macrophages isolated from septic mice is analogous to that observed in endotoxin tolerized monocyte/macrophages, whereby exposure to LPS or other PAMPs dampen the release of inflammatory mediators upon subsequent PAMP re-challenge [11], [26], [27].

For example, macrophages overexpressing TLRs, release higher amounts of inflammatory mediators upon TLR engagement [ 37, 38].

Influx of macrophages, T cells, mast cells and other untested inflammatory cells in adipose tissues releases pro-inflammatory mediators upon development of chronic caloric excess-driven obesity.

Common for these cells is the ability to secrete inflammatory mediators upon activation by rather unspecific stimuli from microbial and other agents.

Basophils and mast cells are similar in terms of expression of the high-affinity IgE receptor and the secretion of cytokines and inflammatory mediators upon stimulation.

More recently, evidence suggests that ROS could serve as paracrine signaling mediators upon pathological stimulation (Love et al., 2013; Niethammer et al., 2009; Wu et al., 2012).

Moreover, this project tries to describe a wide spectrum of immune response mediators upon admission to and release from hospital in CAP patients.

Patients with gastrointestinal food allergy are characterised by increased production of mast cell derived mediators upon allergen contact and present often with unspecific symptoms.