Sentence examples for mediator that exerts from inspiring English sources
In mammals, NO is a signalling mediator that exerts a wide range of key physiological functions.
Anandamide (AEA) is an endogenous lipid mediator that exerts several effects in the brain as well as in peripheral tissues.
It is released from membranes by phospholipase A2 and converted into various lipid mediators that exert many physiological actions [ 17- 19].
Apart from direct oxidative reactions, neutrophils could influence vascular function through release of mediators that exert direct vasoactive effects, including cytokines, adenosine, proteases, and phospholipases.
Endocannabinoids (EC) are neuromodulatory lipid mediators that exert their effects mainly by activating cannabinoid receptor type 1 (CB1) and type 2 (CB2) [ 7].
Obviously, since the host-defense mechanisms are sustained by an enormous network of pro- and anti-inflammatory mediators that may exert antagonist and/or synergic biological activities, further studies are required to better characterize the role of C. verbenacea in the modulation of immune-inflammatory responses when periodontitis is present.
Moreover, a number of recent studies support the view that sphingosine 1-phosphate (S1P), another powerful sphingoid mediator that can be generated by further metabolism of ceramide, exerts a critical role in myogenesis.
The pro-inflammatory mediator IL-1 consists of 4 molecular species (IL-1α, IL-1β, IL-1γ and IL-1δ) that exert similar biological activity through IL-1 receptor (IL-1R) type I.
In recent publications we have reported that, in response to IR, PBMCs are able to release paracrine factors that exert immune modulatory functions and have presented evidence that IR-induced apoptosis is responsible for the release of these paracrine mediators [ 32, 36– 40].
Recent studies have identified n-3 PUFAs as precursors of a distinct set of lipid mediators that probably act through distinct receptors to exert their anti-inflammatory effects.
Phosphorylated Akt (pAkt) exerts an immense variety of functions by targeting downstream mediators that regulate processes such as survival and proliferation.
