Sentence examples for mediator that controls from inspiring English sources

The concept of a lipid mediator that controls neutrophil recruitment is not new.

GSK3β is regarded as an important mediator that controls level of c-FLIP, a caspase-8 inhibitor [ 17].

STAT1 is a signal mediator that controls functions of cell death in the context of interferon-dependent signalling, where it is involved in pro-apoptotic and anti-proliferative signalling pathways (Kim and Lee, 2007).

However, the stimulating effects of insulin and IGF-1 on IGFBP-3 expression in liver macrophages essentially require the presence of hepatocytes indicating that upon stimulation with insulin or IGF-1, hepatocytes release a soluble mediator that controls IGFBP-3 expression in liver macrophages (Villafuerte et al. 1994; Scharf et al. 1996).

Macrophages and neutrophils, in particular, play a central role in the inflammatory process by releasing proteins and small-molecule inflammatory mediators that control infection but can damage host tissue.

Although this claim is beyond the scope of this paper, it may be worth investigating other upstream mediators that control p38 MAPK, ERK, and AKT simultaneously such as TGF-beta, H-ras, and ASK-1, which are known to be involved in wound healing.

Nonetheless, the key mediators that control inflammatory cell recruitment and activation in this process remain to be elucidated.

However, information regarding the key mediators that control the migratory activities of the cancer cells remains largely unknown.

An appreciation of these endogenous pathways and mediators that control timely resolution opened a new terrain for therapeutic approaches targeted at stimulating resolution of local inflammation.

Identifying endogenous mediators that control mTOR/autophagy signalling and, ultimately, the fate of articular cartilage chondrocytes will help generate new therapeutic strategies to modulate cartilage homeostasis and counteract cartilage degeneration.

Furthermore, Srikantan et al. have recently identified the RNA-binding protein HuR and the microRNA miR-548c-3p as the crucial mediators that control TOP2A expression levels and determine the effectiveness of doxorubicin [ 53].