Sentence examples for mediator that affects from inspiring English sources

OEA, an anorectic mediator that affects lipid and glucose metabolism, activates PPAR-alpha [ 133].

29 The important mediator that affects RRM1 to regulate cellular signaling, survival, and migration is phosphatase and tensin homologue.

Our study also substantiates the importance of physical activity as a behavioral mediator that affects both health conditions and quality of life.

Our recent research was been based on the hypothesis that histamine is one of the earliest and potent inflammatory mediators that affects the host immune response to Plasmodium parasites.

The objective of pharmacotherapy is to counteract the underlying pathology of obesity, which is the dysregulation of physiologic mediators that affect appetite and satiety.

This review will focus on experimental approaches currently under study that may lead to elucidation of effective strategies for therapy in OA, with emphasis on mediators that affect the function of chondrocytes and interactions with surrounding tissues.

Several additional mediators that affect chondrocyte metabolism have been described.

Oral microorganisms inevitably up-regulate cytokines and other inflammatory mediators that affect the complex metabolic pathways and may thus be involved in carcinogenesis [ 46].

Tumor-associated immune cells, as well as tumor cells themselves, are the major sources of mediators that affect the functional properties of TAMs.

A second class of mediators that affect insulin sensitivity in both muscle and liver and which are derived from adipose tissue are adipokines.

The key mediator is Tor, a negative regulator of autophagy activated by the Class I PI3K signaling pathway that affects phosphorylation and repression of Atg1.