Sentence examples for mediator structure from inspiring English sources

Activator Mediator binding alters Mediator structure, and these activator-induced structural shifts appear to play key roles in regulating transcription.

Here we summarize these achievements and list open questions on Mediator structure and mechanism.

A similarity in appearance and conformational behavior of yeast and murine complexes indicates a conservation of Mediator structure among eukaryotes.

However, around 80% of the Mediator structure remains unknown and details on the Mediator Pol II interface are lacking.

Conservation across eukaryotes of Mediator structure, subunit organization, and RNA polymerase II interaction suggest conservation of fundamental aspects of the Mediator mechanism.

It appears that activator-induced changes in Mediator structure facilitate promoter escape and the switch to elongating state.

Within the context of a hierarchy, the focus is on the workstation level and, in particular, the construction of a re-configurable system having production agents, error recovery agents, and a mediator agent structure connecting production and recovery agent hierarchies.

General transcription factors could further contribute to alterations of the human Mediator RNAPII structure, as it was observed for TFIIF.

Structural and biochemical data indicate that conformational heterogeneity and dynamics is essential for the organization of Mediator's structure and its regulatory mechanisms.

This might also implicate that the different TFs interact with different subunits, and thus have a different modulatory effect on Mediator's structure.

The interface between the Head and Middle modules is indeed important, facilitating a reorganization of Mediator's structure and inducing a conformation compatible with RNAPII binding.