Sentence examples for mediator of programmed from inspiring English sources
In a previous study, we had identified ceramide generated by the lipase A-SMase as an important mediator of programmed necrosis acting downstream of RIPK1 [ 3].
Caspases are crucial mediator of programmed cell death (PCD).
A particular focus has been on the adipokine leptin (a proinflammatory signal in adipose tissue) as a mediator of programmed changes in the regulation of appetite and metabolism.
Autophagy has emerged as a powerful mediator of programmed cell death, either opposing or enhancing apoptosis, or acting as an alternative form of programmed cell death, different from apoptosis [ 14].
Another enzyme called poly(ADP-ribose) polymerase 1 (PARP-1), a mediator of programmed necrosis activated by oxidative stress, is an important activator of caspase-independent cell death (Zhang et al. 1994).
One class of genes that has been considered a potential target or mediator of programming events is imprinted genes, because these genes critically depend upon epigenetic modifications for correct expression and because many imprinted genes have roles in controlling fetal growth as well as neonatal and adult metabolism.
Complementary analysis suggests that self-assessed relative poverty (as measured by comparison to other households in the community) is a more important mediator of program effects on happiness than absolute poverty (as measured by household consumption expenditures).
This review will discuss maternal metainflammation as a mediator of programming in insulin sensitive tissues in offspring.
In this study the effectiveness of OVK will be tested and possible mediators of program effects will be focus of study as well.
Motivation to quit as defined by constituents of the energy/direction model of motivation appears to be a plausible mediator of cessation program effects.
There is also accumulating support for the role of epigenetic regulation of gene expression as a mediator of the programming of adult-onset metabolic disease.
