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Inflammation is a proximate mediator of preterm birth and fetal injury.
The strong correlation of cervical ferritin with other inflammatory markers provides support for the hypothesis of infection as a mediator of preterm delivery.
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Maternal stress, in the absence of other mediators of preterm birth such as infection, results in increased levels of biological effectors of stress including cortisol and epinephrine, which could activate placental CRH gene expression.
The papers presented in this collection provide an overview of the current state of research in the field of preterm labour in Europe, covering diverse areas such as mechanisms and mediators, methods of prediction and prevention, and new drug development.
Indeed, elevated levels of inflammatory mediators (eg, interleukin-6, tumor necrosis factor) in midtrimester amniotic fluid have been found in cases of preterm delivery and/or spontaneous abortion.
The vast majority of preterm births, about 70percentt, are in this late-preterm category.
The rate of preterm births has increased over the last 20 years.
Many of the interventions have in fact led to higher rates of preterm babies.
In your practice, you treat women with a high risk of preterm delivery.
Along with the twins factor, researchers have identified three other causes of preterm births: vaginal infections, uterine bleeding and stress.
The rate of preterm births among black women is 1.5 times that of whites, according to the March of Dimes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com