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If this relationship does not remain, it could be determined whether delirium is a confounder or a mediator of mortality.
In addition, endothelial dysfunction is associated with the development of multiple organ dysfunction syndrome (MODS) [ 8], which is a major mediator of mortality in ARDS [ 9].
Patients with localized prostate cancer possess a favorable 5-year survival rate, whereas patients with metastatic cancer have a median survival of only 12 15 months, which is an indication that PCa cell metastasis is the primary mediator of mortality for this disease [ 36].
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No clear evidence points to specific drugs, drug combinations, or weight gain as mediators of mortality during intensive therapy to date, but analyses continue.
The findings of this study will assist in identifying vulnerable groups at risk for early mortality, identifying potential mediators of mortality differences, and stimulating quality improvement efforts to improve outcomes for younger women with STEMI.
Is it possible that isolated severe hypoglycemia, not preceded by minor hypoglycemia, could be a mediator of excess mortality in the individuals attempting intensive treatment but continuing to have elevated A1C?
Nonsurvivors displayed the same increase in respiration as survivors arguing against mitochondrial respiratory dysfunction and defect mitochondrial biogenesis, in PBICs, as a mediator of increased mortality in the septic condition.
Initial measures of serum noradrenaline verified an inverse relation between serum levels and mortality, which was initially hypothesized to be a hormonal marker of hemodynamic stress, and later with the appreciation of the value of beta blockers to improve morbidity and mortality in heart failure, felt to itself be a mediator of the increased mortality rates [ 47, 48].
Increased LV mass is an almost universal finding by late-stage CKD and is recognized as an important mediator of morbidity and mortality due to heart failure and lethal arrhythmia, the commonest modes of death in CKD.
Behaviorally, smoking was the strongest mediator of the divorce-mortality link.
In 1999, Wang and colleagues [ 12] identified HMGB1 as a cytokine-like mediator of lipopolysaccharide (LPS -induced mortaLPS -induced.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com