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Leptin has been postulated to be a key mediator linking obesity and hyperuricemia as a potential regulator of SUA level.
Epigenetic studies suggest that DNA methylation is a possible mediator linking individual response to stress and psychopathology and could be considered as a potential biomarker of stress-related mental disorders.
Of note, cortisol was no longer supported as a mediator linking physical danger to birth timing after adjusting for sleep quality and hours awake prior to venipuncture (ab = 0.02, 95% CI [−0.0001, 0.046]).
Leucocytes are a major source of enzymatically active NAMPT, which may serve as a biomarker or even mediator linking obesity, inflammation and insulin resistance.
This study explored the hypothesis that VEGF may be possible mediator linking depression and dementia and might be involved in the cognitive impairment in AD.
While cardiac autonomic nervous system (ANS) dysfunction has been considered as a complication of MetS and a potential mediator linking MetS and adverse cardiovascular events [ 2, 3].
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Gli-2, a hedgehog pathway mediator linked to EMT [ 69], failed to alter the CD44 and CD24 phenotype of MCF-10A cells.
However, few studies have examined the mediators linking these variables.
Alarmins represent nothing less than the proximal endogenous mediators linking cell necrosis and the inflammatory response generated by tissue injury.
Taken together, we hypothesized that loneliness and psychological distress may pose as parallel mediators linking exposure to interpersonal violence to recurrent headache, whereas family cohesion and sex may serve as moderators buffering pathways.
Several adipose-derived adipokines have been demonstrated as mediators linking obesity to insulin resistance, dyslipidemia and inflammation [1].
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