Sentence examples for mediator in response from inspiring English sources

The cytokine interleukin-1 beta (IL-1β) is a potent inflammatory mediator in response to infection, and can be used as an immunological adjuvant.

Control of HIV-1 infection has also been linked to polyfunctional reactivity of memory CD8+ T cells, i.e., T cells that produce more than one immune mediator in response to HIV-1 antigens [4], particularly Gag [5], [6], [7], [8].

Notably, we found that Cav-1 could be up-regulated within 30 min following IR treatment (Fig. 1), earlier than the 24 h shown by Cordes et al [33], suggesting that Cav-1 may act as a sensor and early mediator in response to DNA damage.

IF double staining of GRP78 and PUMA also indicted that PUMA was an apoptotic mediator in response to ER stress in human PHG.

Since this defect was also observed in UNC93b1-mutant cells, it is likely that TLR7 and/or TLR9 signalling stimulate release of this particular mediator in response to NSV.

VIP inhibits these immune mediators by affecting transcriptional regulators such as NFκB and activator protein 1 which transcribes genes responsible for the production of inflammatory mediators in response to pathogens or cytokines.

M1 macrophages are characterized by production of high levels of inflammatory mediators in response to stimulation by pathogen-associated molecular patterns and/or inflammatory cytokines.

Notch signaling in macrophage regulates expression of pro- and anti-inflammatory mediators in response to macrophage activating signals such as LPS (Hu et al., 2008; Zhang et al., 2010; Zhang et al., 2012; Monsalve et al., 2009; Palaga et al., 2008; Tsao et al., 2011; Outtz et al. 2010).

The secretion of inflammatory mediators in response to LPS supports previous observations in murine endometrial epithelial cells [11], [15].

The CD8+ T cells expressed more CD107a and IFNγ (in 10/31 combinations of immune mediators) in response to Gag peptide as compared to the other mediators.

Furthermore, stromal and epithelial cells isolated from the endometrium of WT but not Tlr4−/− mice, secreted inflammatory mediators in response to LPS in vitro.