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This suggests that the recombination mediator function of Rad52 is required for Rad51 to exert its effect, and it is this function of Rad52 that is required for EGC.
A mediator function of therapy adherence is conceivable [ 55].
These results clearly suggest recombination mediator function of BRCA2 in RAD51-promoted HR.
This suggests that RPA phosphorylation may regulate the first steps of DSB repair and is necessary for the mediator function of Rad52.
While the mediator function of both Ang-1 and Ang-2 has been well established in preclinical research, only Ang-2 has been identified as a clinically useful biomarker in the critical care arena.
In contrast, when analysing the mediator function of depression (third model), our data revealed gender differences as well: when adding depression to the model, bereavement lost its predictive power in men but not in women.
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GPs rated the mediator function as one of their most common functions.
Presumably, endothelial cells play a pivotal rule in the pathogenesis of sepsis, not only because they may influence the inflammatory cascade but also because, upon interaction with excessive amounts of inflammatory mediators, the function of these cells may become impaired.
These lipid mediators function as components of a complex and untapped chemical signaling system that underlies a fundamentally new paradigm of interaction between host and pathogen.
Interleukin-5 (IL-5) is the key mediator for the function of eosinophil granulocytes, whose deregulation is characteristic of hypereosinophilic diseases and presumably contributes to allergic asthma.
The phenotype of deletion of β-integrin is similar to that of the DKOs, but it is not possible to determine if β-integrin is a key mediator of the function of Numb/NBL.
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