Sentence examples for mediator complex plays from inspiring English sources

Our findings have also provided evidence that the member of the free module in the Mediator complex plays crucial roles in C. neoformans.

The Mediator complex plays an essential role in the regulation of eukaryotic transcription.

In abiotic stress, as in biotic stress, the Mediator complex plays a critical role.

CTCF and cohesin have been shown to be boundary proteins between TADs, while Mediator complex plays important roles in loop formation for correct gene activation [ 20– 26].

Importantly, this interaction was facilitated by the mediator complex which plays a critical and global role in connecting transcriptional co-activator complexes with general transcription factors and the RNAP holoenzyme [30].

This complex is associated with, but is genetically and biochemically distinct from the Mediator complex, and can play both positive and negative roles in transcription [36] [39].

The involvement of RNA Pol II in heterochromatin assembly indicates that the Mediator complex may also play a role in heterochromatin biology.

Recently, it was found that Mediator Complex Subunit25 (mediatesT1) mediates JA signaling and plays important roles in resistance to necrotrophic fungal pathogens.

The Mediator complex has been shown to play an important role in numerous aspects of development and diseased states.

Another, the Arabidopsis AtMED21, a subunit of an evolutionarily conserved Mediator complex that is thought to play a key role in regulating RNA polymerase II activity [ 71], was found to interact with AtHUB1 and play critical roles in disease resistance to necrotrophic fungi and embryo development [ 13].

Specifically, we suggest that the Mediator complex, depending on its subunit composition, plays a crucial role in the recruitment of the AEP complex on specific MLL-target promoters.