Sentence examples for mediator complex participates from inspiring English sources
Mediator complex participates in transcriptional regulation by connecting regulatory DNA sequences to the RNA polymerase II initiation complex.
The Mediator complex also participates in the regulation of chromatin architecture, epigenetic silencing, and mRNA processing.
Mediator complex subunit 12 participates in various molecular pathways, for example, p53 and Wnt/ β-catenin pathways, which have central roles in tumour development (Kim et al, 2006; Galbraith et al, 2010).
Approximately 60% participate in transcription regulatory mechanisms, including the Mediator complex in eukaryotic cells.
The metabolic functions of the Mediator complex have become increasingly significant.
Nevertheless, it is generally believed that the Mediator complex is heterogeneous both structurally and functionally.
The Mediator complex was originally discovered in yeast, but it is conserved in all eukaryotes.
MED15 encodes a small protein that is a component of the Mediator complex [28].
The mediator complex is required for regulation of most RNAP II transcription [45].
This is consistent with the reports of low abundance of the mediator complex [31].
Endogenous TFIID, FLAG-tagged MED26-containing mediator complex, and recombinant TBP were purified as described [6].
