Sentence examples for mediator complex builds from inspiring English sources
The Mediator Complex builds a bridge between TFs and RNA Pol II so that RNA Pol II can interact with adjacent TFs.
One such complex, built in 1998 in Westport, cost $850,000.
The sprawling complex, built in 2000, is its own universe.
In a subsequent step, nuclear receptors interact with a member of the mediator (Med) complex, which builds a bridge to the basal transcriptional machinery (Rachez et al. 1999).
The metabolic functions of the Mediator complex have become increasingly significant.
Nevertheless, it is generally believed that the Mediator complex is heterogeneous both structurally and functionally.
The Mediator complex was originally discovered in yeast, but it is conserved in all eukaryotes.
MED15 encodes a small protein that is a component of the Mediator complex [28].
The mediator complex is required for regulation of most RNAP II transcription [45].
This is consistent with the reports of low abundance of the mediator complex [31].
Endogenous TFIID, FLAG-tagged MED26-containing mediator complex, and recombinant TBP were purified as described [6].
