We therefore performed three-path mediation analyses with two sequential mediators (Fig. 4b).
In addition, moderated mediation analyses with the moderator modality and mediator situational interest confirm the affective mediation assumption with the following two conditional effects.
Next, we performed mediation analyses with N1, N2, P2, and gamma responses as mediators for the combined condition.
To this end, we performed mediation analyses with N1, N2, P2, and gamma responses as mediators based on preselected electrodes and time -frequency) windows (Fig. 3). Figure 5 shows time -frequencyffects for N1, N2, P2, and gamma responses for each condition and Table 2 showindowssecond-level path coeFigcients.
Additional mediation analyses with covariates were performed whenever more than one brain response was found to be a significant mediator to investigate whether these brain responses carried redundant or complementary information.
For mediator analyses, it is important not only that a given treatment (IMHP vs. HP) is associated with the outcome (6-month mortality), but also that the treatment induces changes in mediator plasma concentrations (association path A) and that these changes are associated with the outcome (association path B).
Furthermore, moderator and mediator analyses will be conducted.
18 19 71 To evaluate the influence of specific potential confounders and mediators, analyses were conducted excluding individuals with a history of CHD or stroke at baseline for the overall population and in never smokers, and by baseline smoking status (ever, current, former, and never).
To further explain the relationship between general WE and SI, two mediation analyses were performed with post-war hardships and depression/anxiety as mediators in the framework of Baron and Kenny [ 44].
An extension of the approach termed three-path mediation analyses quantifies the effects of two sequential mediators (Fig. 4b).
