Sentence examples for mediation of both from inspiring English sources

Recent events have highlighted some unsettled ethical quandaries around the online mediation of both tragedy and excessive violence.

The JNK pathway is critical for the mediation of both autophagy and apoptosis.

Since diverse agents had similar effects on the activation of NF-κB and MnSOD gene expression, it was hypothesized that the activation of NF-κB and MnSOD gene expression are closely associated events and that reduced sulfhydryl groups are required for cytokine mediation of both processes [ 9].

IFN-inducible genes are often associated with apoptotic pathways, and some of these factors have been reported to be regulated by BRCA1 [ 45], which is known to participate in the maintenance of genomic integrity through mediation of both DNA repair and apoptosis mechanisms in the breast [ 46, 47].

On the other hand, hypotheses on the glutamatergic system suggest that glutamate is involved in the mediation of both positive and negative symptoms of schizophrenia in the same direction, although the data are inferential regarding drugs are currently in late stage clinical development [ 23].

Finally, the third method (HM) undermines the relevance of centrality and highlights, instead, the importance of mediation both at the local and global levels.

New kind and new functions of ncRNAs are continuously discovered and one of their most important roles is the mediation of environmental signals, both physical and chemical.

With AMPK α1/2 knockdown in NSCLC cells (siRNA) and knock-out models (AMPK α1/2−/−-MEFs), we demonstrate the dependency of those signalling events on AMPK and the key role of this enzyme in mediation of the antiproliferative effects of both MET and IR.

These models indicated a role for T cells, particularly CD4+, in both the mediation of CLL engraftment (Bagnara et al., 2011; Devereux, 2011; Dürig et al., 2007; Shimoni et al., 1999) and the resultant CLL cell disappearance with concomitant evidence of lethal graft-versus-host disease (GvHD) (Bagnara et al., 2011; Devereux, 2011).

Different versions of the relative judgment theory have implicated both discrete-state and continuous mediation of eyewitness decisions.

Also, both actions were blocked by PD98059, showing mediation of the MEK/ERK pathway.