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The first applications of mediating variables were in psychological theories of how stimulus affects response and sociological studies of the transmission of parental social characteristics to their children.
The order in which mediating variables were included in the model was defined by the significance of its association with lung function.
When these private care mediating variables were entered into the fully adjusted Cox proportional hazards model (Model 3, Table 4), the HRs for SES were all reduced, particularly in SES quintile 5 for PTCA and CABG.
When potential mediating variables were added, effects were reduced.
Potential mediating variables were smoking behaviour, alcohol consumption and physical health status.
All of the potential mediating variables were associated with quality of life in 2005.
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Indirect effects of mediating variables are estimated by the confidence intervals constructed through the bootstrapping procedure [ 36].
Indeed, it is essential that we know what mediating variables are relevant for particular outcomes in randomized clinical trials and that we design interventions to optimize change in the mediators of interest.
The first systematic review to analyze treatment affects for LBM across multiple training dosages and potential mediating variables was the study MD Peterson, A Sen and PM Gordon [ 12].
The four conditions outlined by Barron and Kenny for a variable to be considered as a mediating variable were satisfied (Table 5).
One mediating variable is emotion, which may modulate pain through an interaction of valence (pleasant-unpleasant) and arousal (calm-excited).
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