Sentence examples for mediating this phenotype from inspiring English sources

Here, we have investigated the role of TIEG1 in osteoclasts to further determine their potential role in mediating this phenotype.

We also performed microarray experiments in PC12 cells to gain insight into the molecular changes that may mediate this phenotype.

Further work is clearly required to understand how loss of p300 may contribute to tumour development, but there is an abundance of other target proteins with which it can interact that may mediate this phenotype.

Analysis of the complete genomes of the NY99 and KEN WNV has identified a maximum of 11 amino acids (Table 5) and 22 nucleotides from the 3´NCR that could mediate this phenotype (17 ).

However, it is currently unknown which proteins are modified by ARTD10 that could mediate this growth inhibitory phenotype.

Most studies of DAF-16 have focussed on its role in mediating the phenotypes of mutants of the C. elegans insulin/IGF like signalling (IIS) pathway.

The MDR1 gene encoded transmembrane ABC-transporter MDR1/P-glycoprotein can mediate the phenotype of multidrug resistance (MDR), a major obstacle in the clinical management of cancer patients.

Activation of ERK, p38 and JNK in the dying cells suggests that an overly active MAPK signaling pathway may mediate the phenotype.

Although these phenotypes and their resulting dynamics are important, we have little understanding of the proteins that mediate these phenotypes, particularly for species groups where postmating, prezygotic traits are the primary mechanism of reproductive isolation.

Nonetheless, the current reports from the Gould laboratory are consistent with Mcs5a mediating its phenotype through an immune surveillance mechanism within the mammary gland.

Roles of HMGA1 in mediating the malignant phenotype of this cancer are poorly understood.