Sentence examples for mediating this adaptation from inspiring English sources

We suggest that BAG3 has a critical role in mediating this adaptation.

Also the fact that the increased expression of thermogenic and browning genes in Bmp8b TG mice occurred early in the post-weaning phase, when mice are more vulnerable to low temperatures, suggested the physiological relevance of BMP8b mediating the adaptation to cold demands.

HIF-1 target gene members include a stress response gene family that mediates the adaptation of cells/tissues to chronic or acute hypoxia; this family includes glucose transporters, glycolytic enzymes, and angiogenic and haematopoietic growth factors [ 52].

HIF mediates the adaptation of cells and tissues to low oxygen concentrations.

Hypoxia-inducible factor (HIF) is the key transcription factor that mediates the adaptation of cells and tissues to a hypoxic tumor environment.

Hypoxia-inducible factor 1 (HIF-1), a heterodimeric transcription factor that mediates the adaptation of tumor cells and tissues to the hypoxic microenvironment, has attracted considerable interest as a potential therapeutic target.

HIF is known to be upregulated in many human cancers, where it mediates the adaptation to the hypoxic tumor environment resulting from rapid tumor expansion that exceeds the development of new blood vessels.

These changes may lead to the functional divergence of proteins or RNAs that mediate the adaptation to the environment.

Further, LF82Δhfq mutants were non-motile, impaired in cell invasion and highly sensitive to various chemical stress conditions, reinforcing the multifaceted function of Hfq in mediating bacterial adaptation.

However, the mechanisms mediating lysosomal adaptation are largely unknown.

For example, environmental factors may contribute to genetic differentiation by mediating local adaptation that can reduce the fitness of immigrants or promote reproductive isolation.