Sentence examples for mediating these alterations from inspiring English sources

The mechanisms, however, mediating these alterations in transciptome expression are yet to be fully understood.

This would combine whole-body and regional measurements of metabolism and function, evaluating changes in gene expression in tissues such as muscle and adipose tissue, and establishing the role of cytokine and other molecules released from tumours in mediating these alterations in metabolism.

While the host signalling pathways mediating these phenotypic alterations have been studied in considerable detail, the parasite factors involved are largely unknown (reviewed in [10], [11], [12], [13].

The potential role of tumour-derived Dkk-1 in mediating the alterations of osteoblastic and/or osteolytic activity associated with breast cancer however remains to be investigated.

In the same vein, it remains to be determined if maternal cocaine administration at these experimental doses is able to penetrate the placental barrier and alter fetal brain monoamine transmitter levels sufficiently to mediate these types of epigenetic alterations.

We next assessed whether or not IRAK-M mediated the alterations in selected histone PTMs during sepsis.

Increased axoplasmic Ca2+ mediated the alterations in mitochondrial length and transport.

Bioinformatics approaches led to the identification of three main drug-responsive genomic networks and indicated neurobiological pathways that mediate the alterations in transcription.

These data suggest that renal lead-binding proteins may play a role in mediating known alterations in renal gene expression associated with formation of intranuclear inclusion bodies.

However, the role that extragonadal steroid synthesis plays in mediating cardiovascular alterations in specific organs is not clear and requires further investigation.

It is now known that micro RNAs (miRNA) can have a role in mediating such alterations in gene expression through repression or degradation of target mRNAs.