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The family of FcγR mediating these activities includes FcγRI, FcγRIIa, FcγRIIb, FcγRIIIa and FcγRIIIb [60 62].
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Thus, CD4mc are capable of sensitizing HIV-1-infected cells to ADCC and infectious viral particles to neutralization by easy-to-elicit antibodies that are otherwise unable to mediate these activities.
This finding suggests that cholinergic mechanisms may mediate these activities.
Importantly these cells also show significant defects in the production of inflammatory cytokines in response to intact fungal organisms; however, the uptake and killing of these organisms is unaffected, indicating that alternative receptor pathways can mediate these activities.
We have determined the crystal structure of yeast Uba1, revealing a modular architecture with individual domains primarily mediating these specific activities.
This review describes the physiological relevance of paracrine Caspase-3 signalling for developmental processes, tissue homeostasis and tissue regeneration, and discusses the role of soluble factors and microparticles in mediating these paracrine activities.
The complicated role of TGF- β in mediating these cellular activities depends on cell types, growth environment, concentration of ligands and the presence of other growth factors (Hu et al, 1998; Massague, 1998; Savage-Dunn, 2005).
Despite these advances, the extraordinarily complex cellular responses to MYC expression has made it difficult to decipher the target genes that mediate these biological activities.
Depending on cell type and context TWEAK mediates these activities via Fn14 by activating a variety of downstream signaling cascades.
While we generally refer to low or high androgen levels causing a behavior, it is really the concentrations of AR T and AR DHT complexes that mediate these androgen related activities.
These results imply that AFP might play a role in mediating the activity of PTEN in hepatoma cells.
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