Sentence examples for mediating their effects from inspiring English sources

One question raised by these studies is the relation between the expression patterns of Wnts, the erbB ligands potentially mediating their effects, and the metalloproteinases necessary for Wnt-mediated activation of EGFR signalling in breast cancer, and whether any relations identified are correlated with outcome in breast cancer.

To date, the role of HIF in mediating their effects in the placenta has been little studied.

However, further research is still required to determine the mechanisms via which marine PUFAs are mediating their effects.

GPCRs are heptahelical transmembrane receptors mediating their effects via heterotrimeric G proteins (of either the Gs, Gi, Gq, or G12/13 subtypes) [ 5, 6].

The current work therefore points to the need for additional studies to determine the potential pathophysiological roles of KLK7 and KLK9 in glioma malignancy and any parallel involvement of PAR-activation in mediating their effects.

However, other components of fish oil may be detrimental to cancer treatment, and further research is still required to determine the mechanisms by which both marine-derived n-3 PUFAs and other fish-oil derived compounds are mediating their effects.

The applications of engineered zinc finger proteins are discussed in a context of the mechanism mediating their effect on the targeted DNA.

The opioid receptors mediate their effects mainly by inhibiting regeneration of the nerve impulse at the postsynaptic membrane.

These compounds mediate their effects via blockade of cyclooxygenase-1.

Many oncogenes and tumor suppressors mediate their effects by interfering with or inducing apoptotic signaling.

These molecules mediate their effects by binding to two proteins, called CB1 and CB2.