Sentence examples for mediating their effect from inspiring English sources

The applications of engineered zinc finger proteins are discussed in a context of the mechanism mediating their effect on the targeted DNA.

Together, these results suggest that 2q35 breast cancer risk loci may be mediating their effect through IGFBP5.

CAR-T cells can persist and even expand over time, with the consequence of mediating their effects, both therapeutic and deleterious.

Epitranscriptomic RNA modifications can regulate mRNA function; however, there is a major gap in our understanding of the biochemical mechanisms mediating their effects.

To date, the role of HIF in mediating their effects in the placenta has been little studied.

However, further research is still required to determine the mechanisms via which marine PUFAs are mediating their effects.

GPCRs are heptahelical transmembrane receptors mediating their effects via heterotrimeric G proteins (of either the Gs, Gi, Gq, or G12/13 subtypes) [ 5, 6].

Taxanes may partly mediate their effect in castration-resistant prostate cancer (CRPC) through disruption of androgen-receptor trafficking along microtubules.

The cis-acting regulatory sequences in the HIV enhancer that mediate their effect have also been characterized.

Several mechanisms have been proposed for the ability of tumor antibodies to mediate their effect in vivo.

These novel repressors may mediate their effect via direct / indirect regulation of SCAP, via repressing SREBP transport or by modulating INSIG1 levels.