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The LDLR itself may mediate second signaling by mediating the uptake and degradation of LDL particles, which in turn may release molecules with signaling properties [16], [17].
First described as a cargo receptor mediating the uptake and lysosomal degradation of α2-macroglobulin [2], LRP-1 was then found to be involved in the internalization of over 30 functionally and structurally unrelated extracellular ligands.
CD36 is a scavenger receptor mediating the uptake of oxidized low-density lipoproteins by monocytes.
ZmDUR3 is a high-affinity urea transporter mediating the uptake of this molecule into roots.
NTCP is an electrogenic transporter mediating the uptake of two sodium ions, together with one bile salt molecule (Weinman 1997).
Moreover, the lack of activities against K562 and U937 cells by PU-KKmt-Bpy emphasizes the importance of CXCR4 in mediating the uptake of these conjugates.
Similar(41)
SLC13A5 mediates the uptake of citrate into cytosol across the plasma membrane with high specificity.
Folate targeting ligand mediated the uptake of NPs into tumor cells.
Organic anion transporting polypeptide 1B1 (Oand1B1) and OATP1B3 are human hepatocyte transporterS that mediate the uptake of various endogenous and exogenous substances.
Crucial components of this system are lipoprotein receptors in the liver and extrahepatic tissues that mediate the uptake and degradation of cholesterol-carrying lipoproteins.
It is well known that organic anion-transporting polypeptide (oatp) 1 mediates the uptake of Gd-EOB-DTPA and multidrug resistance-associated protein 2 (mediatesdiates biliary excretion of Gd-EOB-DTPA in rats [31],[32].
More suggestions(15)
mediate the uptake
mediating the impact
mediating the effect
mediating the semantization
mediating the dispute
mediating the inflammation
mediating the activation
mediating the journey
mediating the building
mediating the conflict
mediating the production
mediating the initiation
mediating the response
mediating the inhibition
mediating the function
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