Sentence examples for mediating the toxicity from inspiring English sources

The Aryl hydrocarbon receptor (Ahr) is the nuclear receptor mediating the toxicity of dioxins -widespread and persistent pollutants whose toxic effects include tumor promotion, teratogenesis, wasting syndrome and chloracne.

Free radical formation in heme proteins is recognized as a factor in mediating the toxicity of many drugs.

We demonstrated the involvement of mitogen-activated protein kinase (MAPK) extracellular signal-regulated kinase-1/2 (ERK1/2) and c-Jun N-terminal kinase (JNK) pathways in mediating the toxicity induced by Tat and morphine and also observed significant neuroprotective effects of PDGF-BB against HIV-Tat and morphine mediated combined toxicity.

The molecular pathways mediating the toxicity of TCDD are also likely to be more extensive than the impairment of AP-1 signaling.

Since TrxR is critical for cellular antioxidant defense system the inhibition of this enzyme likely has a central role in mediating the toxicity of MeHg.

While it is thought that the immune system is involved in many of these reactions, the mechanisms or the proteins that may be mediating the toxicity remain elusive.

Further analysis is required to further identify the SRD molecules and the biological mechanism by which they mediate the toxicity associated with acute radiation sickness.

Tau, an important pathological protein of Alzheimer's disease (AD), can mediate the toxicity of amyloid β (Aβ).

The aryl hydrocarbon receptor (AHR) mediates the toxicity of some PAHs.

Western blotting further showed the gas plasma treatment degraded the A subunit, which mediates the toxicity of Stx.

The zebrafish (Danio rerio) has three identified AHRs: AHR1A and AHR1B, the roles of which are not yet well elucidated, and AHR2, which has been shown to mediate the toxicity of various anthropogenic compounds including dioxins, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs).